We are looking for an enthusiastic master student within the AI for Parkinson Lab. This lab, embedded in the Centre of Expertise for Parkinson’s and Movement Disorders at Radboudumc, focusses on the development of digital markers for Parkinson’s disease (PD) progression. One of the hallmark symptoms of PD is tremor, mostly seen in the arm at rest. Using a wrist-worn gyroscope sensor and a tremor detection algorithm [1], we can measure tremor continuously in daily-life.
As part of the Personalized Parkinson Project [2] we have collected 2 years of sensor data of around 600 persons with PD, enabling the assessment of tremor progression over this period. The aim of this project is to investigate the influence of seasonality and/or the start of the covid-19 pandemic on tremor progression. This could enhance our understanding of tremor pathophysiology and ultimately improve quality of care.
Contact: Gabriel Bucur (RU); Nienke Timmermans (Radboudumc);
[1] N. A. Timmermans e.a., ‘A generalizable and open-source algorithm for real-life monitoring of tremor in Parkinson’s disease’, npj Parkinsons Dis., vol. 11, nr. 1, p. 205, jul. 2025, doi: 10.1038/s41531-025-01056-2. https://www.nature.com/articles/s41531-025-01056-2
[2] B. R. Bloem e.a., ‘The Personalized Parkinson Project: examining disease progression through broad biomarkers in early Parkinson’s disease’, BMC Neurol, vol. 19, nr. 1, p. 160, jul. 2019, doi: 10.1186/s12883-019-1394-3. https://pubmed.ncbi.nlm.nih.gov/31315608/